Meng ZY, Song WQ (2017) Low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarction. Neural Regen Res 12(4), 610-613.
The authors investigated whether low frequency (1Hz) rTMS to the contralesional M1 might improve functionality after stroke. This protocol was based on the theory that inhibiting the contralesional M1 can reduce excessive inhibition over the damaged M1 and allow for improved recovery. 20 patients with cerebral infarction of the internal carotid artery were randomly assigned to receive 30 minutes of active rTMS or sham over 14 days, alongside physical rehabilitation. Both groups showed significant improvements compared to baseline across stroke impairment scores (National Institute of Health Stroke Scale), performance of activities of daily living (Barthel Index), and motor functions (Fugl-Meyer Assessment). However, the active rTMS group had significantly greater improvements compared to the sham control group. No severe adverse reactions were reported, only brief dizziness in one participant in the active rTMS group.
*For original abstract/publication see the link below.
Publication link: https://europepmc.org/article/med/28553342