Scientific & Research Studies
Read the latest research articles and studies exploring the use of TMS in various disorders.
This section of the Knowledge Center provides examples of clinical research relating to the below psychological and neurological conditions. These research examples are provided for interest only and do not serve as a clinical guide or recommendation.
Scientific content remains the intellectual property of the authors. Magstim does not engage in generating, or editing scientific content presented in this Knowledge Center. Inclusion in the Knowledge Center should not be taken as an endorsement of scientific findings by Magstim. Please note: the use of Magstim devices for other than the cleared intended use is considered investigational.
Post-traumatic Stress Disorder (PTSD)
Meta-analysis of repetitive transcranial magnetic stimulation (rTMS) protocols in post-traumatic stress disorder (PTSD)
This meta-analysis reviewed the data from 11 studies investigating rTMS treatment in PTSD, covering 217 patients in active rTMS and 160 sham-controls.
Pain
The effects of repetitive transcranial magnetic stimulation (rTMS) on chronic lower back pain
In this open-label, sham-controlled study, participants with chronic lower back pain were randomized to receive active rTMS (n = 44), sham (n = 12), or physical-therapy (n = 26).
Pain
The effects of repetitive transcranial magnetic stimulation (rTMS) on fibromyalgia symptoms
In this randomized, double-blind, sham-controlled study, participants with persistent (≥6 months) widespread pain resulting from fibromyalgia received either 10Hz rTMS (n = 15) or sham (n = 15) over the left M1.
Pain
The effects of intermittent theta burst stimulation (iTBS) on neuropathic pain
In this randomized, sham-controlled study, the authors investigated the effects of five days of once-daily intermittent theta burst stimulation (iTBS) on neuropathic pain.
Major Depressive Disorder (MDD)
Long-term effectiveness of repetitive transcranial magnetic stimulation (rTMS) in major depressive disorder (MDD)
This naturalistic, observational study examined the effectiveness of rTMS in pharmacoresistant MDD over a 12 months follow-up period in 257 patients.
Stroke Rehabilitation
High-frequency repetitive transcranial magnetic stimulation (rTMS) over the ipsilesional primary motor area (M1) after acute unilateral stroke
This randomized, double-blind, sham-controlled trial investigated the effectiveness of high frequency (5Hz) rTMS applied over the ipsilesional M1 for supporting functional recovery after stroke (unilateral infarction in the middle cerebral artery territory).
Stroke Rehabilitation
Low frequency repetitive transcranial magnetic stimulation (rTMS) over the contralesional primary motor area (M1) in stroke rehabilitation
The authors investigated whether low frequency (1Hz) rTMS to the contralesional M1 might improve functionality after stroke.
Addiction
The effects of repetitive transcranial magnetic stimulation (rTMS) on cocaine addiction
In this small pilot study individuals with cocaine addiction were randomly assigned to receive either standard pharmacological therapy (control group, n = 16) or 8 sessions of high-frequency (15Hz) rTMS over the left DLPFC (n = 16).
