For many people coping with Major Depressive Disorder (MDD) antidepressants have proven to provide adequate symptom relief enabling them to resume the life they once enjoyed. However, some patients experience a form of MDD known as TRD when standard medications provide little to no relief.
If you think this sounds familiar you should discuss and answer the following questions with your doctor:
¹Ionescu, D. F., Rosenbaum, J. F., & Alpert, J. E. (2015). Pharmacological approaches to the challenge of treatment-resistant depression. Dialogues in clinical neuroscience, 17(2), 111–126.
²Rush, A. J., Trivedi, M. H., Wisniewski, S. R., Nierenberg, A. A., Stewart, J. W., Warden, D., Niederehe, G., Thase, M. E., Lavori, P. W., Lebowitz, B. D., McGrath, P. J., Rosenbaum, J. F., Sackeim, H. A., Kupfer, D. J., Luther, J., & Fava, M. (2006). Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. The American journal of psychiatry, 163(11), 1905–1917. https://doi.org/10.1176/ajp.2006.163.11.1905